DATASET ON INSIGHTFUL BIO-EVALUATION OF 2-(QUINOLINE-4-YLOXY)ACETAMIDE ANALOGUES AS POTENTIAL ANTI-MYCOBACTERIUM TUBERCULOSIS CATALASE-PEROXIDASE AGENTS VIA IN SILICO MECHANISMS

Dataset on insightful bio-evaluation of 2-(quinoline-4-yloxy)acetamide analogues as potential anti-Mycobacterium tuberculosis catalase-peroxidase agents via in silico mechanisms

The continuous havoc wrecked by tuberculosis among humans worldwide remains colossal.In this work, twenty-one (21) 2-(quinoline-4-yloxy)acetamide analogues were observed against Mycobacterium tuberculosis tinsupe catalase-peroxidase (This enzyme shields bacteria from poisonous drug-like molecules) (PDB ID: 1sj2) using density functional theory meth

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Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

Summary: Neutrophils are phenotypically heterogeneous and exert either anti- or pro-metastatic cimilre s6 adjustable breast pump functions.We show that cancer-cell-derived G-CSF is necessary, but not sufficient, to mobilize immature low-density neutrophils (iLDNs) that promote liver metastasis.In contrast, mature high-density neutrophils inhibit th

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